lunes, 18 de enero de 2016

Alternative Mesothelioma Treatments – An Overview

How does one acquire mesothelioma? 

 Mesothelioma is a unique type of cancer. It is not like other cancers which are genetically linked. It is acquired from the environment through exposure of the body to asbestos. Typically, miners who formerly worked in an asbestos mining have this type of cancer. Asbestos is a mineral that is mined for its durability, flexibility and resistant capacity. Asbestos threads are woven together and made into materials which resist chemicals and extreme heat. Many factories and construction engineers use this material. Asbestos mining is banned from many countries today. Still, many are mining and using it as a prime material for chemical and power plants. 

 Different alternative treatments for mesothelioma Anti-angiogenesis therapy. This type of therapy directly affects the blood flow. As you know, cancer cells and tumors started as a single cell that developed into a large mass of tumor over time. How is this so? Cells need blood to thrive, grow and develop. The blood is responsible to give oxygen and nutrition to the cells to keep them healthy. Abundance of blood vessels along the cell pathways makes them very much alive. By cutting the blood supply, the cells will lose the nutrients and oxygen they need in order to grow. This principle is called angiogenesis. Diverting blood supply from a certain group of cells by cutting the blood vessels is called anti-angiogenesis. Gene therapy. 

This therapy modifies the chromosome, RNA and DNA which results a properly arranged nucleic acids. Defective gene means defective proteins. This is the root of genetic disorders such as liver cancer, hemophilia and other genetic mutations. Since, mesothelioma is not a genetic disorder, gene therapy uses virus by modifying its genetic structure and inject it to the tumor. The modified virus contains drug which is toxic to the cancer cells but not harmful to normal cells. This way, the cancer cells will die. This innovative cell-targeting technique is found to be very effective in so many trials already. This new scientific breakthrough gives new efficiency in curing mesothelioma. Immunotherapy. 

This is a type of manipulation of the immune system. The human immune system kills only foreign bodies like bacteria, viruses and other foreign cells. In the case of cancer, immune system does not recognize it as foreign bodies because it is produced by the person’s own body. What immune therapy does is that it helps the immune system to recognize the difference between defective and normal cells. Immunotherapy in mesothelioma involves administering vaccines. Typically, vaccines are given to prevent diseases. In mesothelioma, vaccines are given to remove existing cancerous cells and malignant tumors in the body. 

The vaccine is made up of cancer cells from which are the patient’s own. These defective cells are modified in the laboratory and made into antigens. The modified cells will then be injected back to the patient. This technique helps the immune system to recognize which cells are cancerous and which are normal. Finding ways in combating tumors like mesothlioma has come a long way. Alternative ways of treatment has come from the organ therapy up to the genetic and molecular level. Modern medicine is continually searching for the best cure for tumors. 

Alternative mesothelioma treatments are giving new ways to effectively eliminating such disease.

jueves, 7 de mayo de 2015

What is asbestos?


 
What is asbestos? 

Asbestos is the term used for a naturally occurring mineral that resembles a rock in its natural form. The rock is then split into fibers, which are resistant to heat, fire, and chemicals. These natural properties made it a popular commercial product used indiscriminately in the United States until the late 1970s. The fibers once woven into fine thread can become brittle and can then float in the air, where they can be inhaled, land on and stick to clothing, and found on exposed surfaces of a person's body who has been exposed to these fibers. 


Can mesothelioma be prevented?

 Can mesothelioma be prevented? 


Avoiding exposure to asbestos is the best way to prevent the development of mesothelioma. The Occupational Safety and Health Administration (OSHA) is the federal agency responsible for developing safety regulations for workers who come into contact with asbestos. Employers are required to follow these regulations and to ensure that their workers have adequate education about safety and the use of protective equipment.



What causes mesothelioma?




We know that exposure to asbestos causes mesothelioma. This has been proven in the research laboratory, as well as in animal experiments and in studies of exposed human beings. Recently researchers at Mt. Sinai Hospital in New York City reviewed the autopsies of 2,015 patients who died between 1883 and 1910. This review did not reveal any cases of tumors that resembled mesothelioma, apparently due to the fact that asbestos was not in generalized use during this period of time. This adds to the mounting evidence that asbestos is a key factor in the development of this disease. 



What are the risk factors, or who gets mesothelioma?

What are the risk factors, or who gets mesothelioma? 

Anyone can get mesothelioma; it occurs across all races and genders and is found in young and old alike. The dominating risk factor in developing mesothelioma is exposure to asbestos. The risk is greatly increased in people who have had repeated exposure to asbestos for prolonged periods of time. The majority of people who develop this disease can trace their exposure back to jobs where they encountered asbestos. Thirty percent of all mesothelioma patients are navy veterans having been exposed in the boiler room of the ships or working in the shipyards. Other highrisk professions include brake repair workers, construction workers, those who worked with or manufactured insulation materials, and people who work in asbestos abatement (removal of asbestos). 




We often talk of "secondhand" exposure, which would affect those who came into contact with mesothelioma through asbestos fibers brought home on workers' clothing and equipment. Many people are exposed at home, schools, or office buildings during renovation projects.

What are the pleura?



What are the pleura?
In pleural mesothelioma the initial site of disease is most often the pleura, an important thin membrane that lines the inside of the chest wall (parietal pleura), or the visceral pleura, which lines the lungs. The pleura is a sheetlike lining formed by rectangular cells called mesothelial cells, and is usually not more than a few layers thick. If unaffected by disease, it is comparable in thickness to that of a blown-up balloon membrane. There are two pleuras in the chest. The parietal pleura lines the inside of the chest wall like wallpaper, covering not only the inside of the ribs but also the diaphragm and pericardium. 

Are there different types of mesothelioma?


Are there different types of mesothelioma? 

Looking under the microscope, the pathologist is able to distinguish three distinct types of mesothelioma based on the appearance of the cells. The majority of mesothelioma is of the epithelial type, which, under the microscope, resembles adenocarcinoma cells (like those found in lung cancer).